李亚兵;

• 1:西安邮电大学计算机学院

摘要(Abstract)：

随着生活节奏的不断加快,睡眠障碍已成为当今社会最常见的疾病,并且患病率逐年升高。如何实现睡眠障碍的临床评估与诊断,探索睡眠障碍的评估方案已成为医学、信息处理等交叉领域的研究热点和急需解决的问题。基于国内外文献检索,综述了睡眠障碍研究的最新进展,并对存在问题及发展方向进行展望。

关键词(KeyWords)： 睡眠障碍;临床评估;神经影像学磁共振成像

Abstract:

Keywords:

基金项目(Foundation): 西安邮电大学博士启动基金项目(205020018)

作者(Author): 李亚兵;

Email:

DOI: 10.13682/j.issn.2095-6533.2020.06.009

参考文献(References)：

• [1] 中华医学会神经病学分会.中国成人失眠诊断与治疗指南(2017版)[J].中华神经科杂志,2018,51(5):324-335.DOI:10.3760/cma.j.issn.1006-7876.2018.05.002.
• [2] 严雯,彭小兰,司江华.睡眠障碍的神经影像学研究进展[J].世界最新医学信息文摘,2018,18(54):39-40.DOI:10.3969/j.issn.1002-0829.2005.06.015.
• [3] 程德均.失眠的中西医诊疗研究进展[J].世界最新医学信息文摘,2019,19(16):74-75.DOI:10.19613/j.cnki.1671-3141.2019.16.036.
• [4] DAI X J,NIE X,LIU X,et al.Gender differences in regional brain activity in patients with chronic primary insomnia:Evidence from a resting-state fMRI study[J].Journal of Clinical Sleep Medicine,2016,12(3):363-374.DOI:10.5664/jcsm.5586.
• [5] SPIEGELHALDER K,REGEN W,BAGLIONI C,et al.Neuroimaging insights into insomnia[J].Current Neurology and Neuroscience Reports,2015,15(3):1-9.DOI:10.1007/s11910-015-0527-3.
• [6] DELROSSO L M,MARTIN K,BRUNI O,et al.Sleep disorders in children with incidental pineal cyst on MRI:A pilot study[J].Sleep Medicine,2018,48:127-130.DOI:10.1016/j.sleep.2018.05.003.
• [7] ZHAO L,WANG E,ZHANG X,et al.Cortical structural connectivity alterations in primary insomnia:Insights from MRI-based morphometric correlation analysis[J].BioMed Research International,2015(2015):1-23.DOI:10.1155/2015/817595.
• [8] JOO E Y,KIM J S,NOH H J.Brain gray matter deficits in patients with chronic primary insomnia[J].Sleep,2013,36(7):999-1007.DOI:10.5665/sleep.2796.
• [9] JOO E Y,SUH S,KIM H,et al.Hippocampal substructural vulnerability to sleep disturbance and cognitive impairment in patients with chronic primary insomnia:Magnetic resonance imaging morphometry[J].Sleep,2014,37(7):1189-1198.DOI:10.5665/sleep.3836.
• [10] MAQUET P.Positron emission tomography studies of sleep and sleep disorders[J].Sleep,1997,244(S1):23-28.DOI:10.1007/bf03160568.
• [11] SMITH M T,PERLIS M,CHENGAZI V U,et al.Neuroimaging of NREM sleep in primary insomnia:A Tc-99-HMPAO single photon emission computed tomography study[J].Sleep,2002,25(3):325-335.DOI:10.1093/sleep/25.3.325.
• [12] SPIEGELHALDER K,REGEN W,PREM M,et al.Reduced anterior internal capsule white matter integrity in primary insomnia[J].Human Brain Mapping,2014,35(7):3431-3438.DOI:10.1002/hbm.22412.
• [13] ELVSASHAGEN T,NORBOM L B,PEDERSEN P,et al.Widespread changes in white matter microstructure after α day of waking and sleep deprivation[J].PLoS One,2015,10(5):e0127351.DOI:10.1371/journal.pone.0127351.
• [14] LI S,TIAN J,BAUER A,et al.Reduced integrity of right lateralized white matter in patients with primary insomnia:A diffusion-tensor imaging study[J].Neuroradiology,2016,28(2):520-528.DOI:10.1148/radiol.2016152038.
• [15] LI Y,WANG E,ZHANG H,et al.Functional connectivity changes between parietal and prefrontal cortices in primary insomnia patients:evidence from resting-state fMRI[J].European Journal of Medical Research,2014,19(1):32.DOI:10.1186/2047-783X-19-32.
• [16] DAI X J,PENG D C,GONG H H,et al.Altered intrinsic regional brain spontaneous activity and subjective sleep quality in patients with chronic primary insomnia:A resting-state fMRI study[J].Neuropsychiatric Disease and Treatment,2014,10:2163-2175.DOI:10.2147/NDT.S69681.
• [17] ALTENA E,WERF Y,SANA-ARIGITA E J,et al.Prefrontal hypoactivation and recovery in insomnia[J].Sleep,2008,31(9):1271-1276.DOI:10.1016/j.seizure.2008.01.009.
• [18] BUYSSE D J,GERMAIN A,HALL M L,et al.EEG spectral analysis in primary insomnia:NREM Period Effects and Sex Differences[J].Sleep,2008,31(12):1673-1682.DOI:10.1093/sleep/31.12.1673.
• [19] SPIEGELHALDER K,REGEN W,FEIGE B,et al.Increased EEG sigma and beta power during nrem sleep in primary insomnia[J].Biological Psychology,2012,91(3):329-333.DOI:10.1016/j.biopsycho.2012.08.009.
• [20] BAGLIONI C,REGEN W,TEGHEN A,et al.Sleep changes in the disorder of insomnia:A meta-analysis of polysomnographic studies[J].Sleep Medicine Reviews,2014,18(3):195-213.DOI:10.1016/j.smrv.2013.04.001.